Sanket Anaokar4th Year Ph.D Candidate
Bayer School of Natural and Environmental Sciences
Patton-Vogt Lab, Mellon Hall
Education:M.S Biotechnology, Duquesne University, 2013
B.Sc Biotechnology, Mumbai University, India, 2010.
Characterization of a novel pathway for phosphatidylcholine biosynthesis in Saccharomyces cerevisiae
Glycerophosphopholipids (phospholipids) are essential components of biological membranes. Several metabolic diseases like diabetes, cancer and obesity can cause increased or decreased levels of certain phospholipids in cellular membranes. Thus, the maintenance of membrane composition is crucial to cell functioning. Phosphatidylcholine (PC) is the major phospholipid found in all eukaryotic membranes. The two main pathways by which PC is synthesized are the methylation pathway and the Kennedy pathway (CDP-DAG pathway). Here we report on the identification of a novel pathway for PC biosynthesis in S. cerevisiae.
Bartosz Głąb, Mirela Beganovic, Sanket Anaokar, Meng-Shu Hao, Allan Rasmusson, Jana Patton-Vogt, Antoni Banaś, Sten Stymne, Ida Lager. Identification and Characterization of Glycerophosphocholine Acyltransferase (Gpc1) in Fungi and Plants; A Novel Dual Function Enzyme in Phosphatidylcholine Synthesis. Manuscript in preparation.
Graduate or Postdoctoral Travel Award for $1000 from ASBMB to present at the ASBMB 2016, San Diego, CA
The ASBMB 2016 Thematic Best Poster Award for Lipid and Lipid Signaling ($333) at ASBMB 2016, San Diego, CA.
S. Anaokar, I. Lager, B. Glab, A. Banas, S. Stymne, J. Patton-Vogt (2016). Characterization of a Glycerophosphocholine Acyltransferase (GPCAT) from Saccharomyces cerevisiae. American Society of Biochemistry and Molecular Biology (ASBMB). (2016 Best Thematic Poster)
J. Patton-Vogt, S. Anaokar, J. Brant, B. Jonik, N. Nesbitt, and M. Vera. A Functional Relationship Between Plb1-mediated Phosphatidylcholine Turnover and Sphingolipid Homeostasis in Saccharomyces cerevisiae.