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Undergraduate Course Descriptions

121, 122. General Chemistry.  4 cr. each

The fundamental principles and concepts of chemistry are presented from the standpoint of atomic and molecular structure with illustrative examples from descriptive chemistry. The basic concepts of thermodynamics, chemical kinetics and equilibrium are introduced. The laboratory portion of the first semester illustrates the principle of ionic equilibria including qualitative inorganic analysis. Prerequisite for 121: Math 105 (College Algebra and Trigonometry) or a Math SAT greater than 500 and/or Math Placement Exam score greater than 17. Toledo Chemistry Placement Exam is required by all students. Prerequisite for 122: C or better in 121. Lecture, three hours; recitation, two hours.

121L, 122L General Chemistry Lab.  1 cr. each

This laboratory introduces students to techniques such as gravimetric analysis, pipeting, performing titrations, and qualitative analysis within the context of the major topics discussed in General Chemistry 121 and 122. The students also learn how to record observations in a laboratory notebook and write a scientific style lab report.

Prerequisites: a C or better in 121L for 122L. 121 must be taken prior to or concurrent with 121L. 122 must be taken prior to or concurrent with 122L. Laboratory, three hours.

121H, 122H. Honors General Chemistry  5cr. each

The fundamental principles and concepts of chemistry are presented from a molecular standpoint. The basic concepts of bonding, molecular structure, intermolecular forces, thermodynamics, chemical kinetics, and equilibrium are introduced with relevant biological and environmental examples. A discovery-based approach format is used in the laboratory. Toledo Placement exam is required. Prerequisite for 122H: C or better in 121H. Lecture, three hours; laboratory, three hours; recitation, two hours.

211, 212. Organic Chemistry  3 cr. each

Students are given a firm foundation in the fundamentals of the structure and reactivity of organic compounds. Emphasis is on the basic mechanistic principles of the reactions and the strategies used to synthesize organic compounds. The use of NMR and IR spectroscopy to identify organic compounds is also emphasized. Prerequisites: a C or better in 122 for 211; a C or better in 211 or 211H for 212. Lecture, three hours.

211H, 212H. Honors Organic Chemistry.  3 cr. each

Students are given a firm foundation in the fundamentals of the structure and reactivity of organic compounds with the use of relevant biological examples. Emphasis is on the basic mechanistic principles of the reactions and the strategies used to synthesize organic compounds. The use of NMR, MS, IR and UV-visible methods in organic chemistry is stressed. Prerequisite: a C or better in 122 or 122H for 211H. Prerequisite for 212H: 211H. Lecture, four hours.

211L, 212L. Organic Chemistry Lab.  1 cr. each

This lab exposes students to basic synthetic and purification techniques used in organic chemistry. Both microscale and macroscale equipment are used. The student acquires a knowledge of the various wet methods of qualitative organic analysis and also learns to generate and interpret IR and NMR spectra. Prerequisites: 211L for 212L. 211 must be taken prior to or concurrent with 211L. 212 must be taken prior to or concurrent with 212L. Laboratory, three hours.

211HL, 212HL Organic Chemistry Honors Lab.  1 cr. each

Students cover the same techniques as the 211L, 212L labs. In the Honors lab students are taught additional techniques useful for undergraduate research. They are permitted hands-on use of various instrumentation such as NMR spectrometer, gas chromatograph, and GC-MS instruments. Students are introduced to the chemical literature. Prerequisites: 211H lab for 212H lab, 211H and 212H must be taken prior to or concurrent with 212H lab. Laboratory, three hours.

230L. Research Laboratory Techniques.  2 cr.

This lab emphasizes the refinement of quantitative analytical techniques and the application of basic statistical methods of data analysis. Students will learn methods of standardization, calibration, titration, and spectroscopy through a series of wet chemical and instrumental experiments. Corequisite: 122. Laboratory, four hours; recitation, two hours.

275. Environmental Chemistry.  3 cr.

Provides students with training in correlation, interpretation, and analysis of related topics and issues involved in environmental chemistry including aquatic, atmospheric, and geochemical interactions. They will receive experience in environmental chemical sampling, modeling and testing methods. Prerequisite: 121, 122, and 211 or 211H.

301. Physical Chemistry for the Life Sciences  4 cr.

This one semester course will present the principles of physical chemistry and its application in the life and forensic sciences. Areas that will be covered include enthalpy, entropy, free energy, chemical and biochemical equilibria, red ox chemistry, kinetics and spectroscopy. Illustration of how these principles are applied to fundamental problems in the life sciences, forensic sciences, and biochemistry will be made.

Prerequisite: 212 or 212H. Lecture 4 hours.

312. Inorganic Chemistry I - 3 cr.

A survey of the basic principles required for understanding inorganic chemistry including molecular structure, periodic trends, bonding models, crystal structure, and the 18-electron rule, as well as aqueous and non-aqueous solvents. These principles will be applied principally to the main-group elements and their compounds. An introduction to molecular symmetry and transition metal chemistry will also be provided. Prerequisite: a C or better in 321 (or 301). Lecture, three hours.

321, 322. Physical Chemistry.  4 cr. each

A study of the structure and properties of the various states of matter, thermodynamics, thermochemistry, kinetics and an introduction to quantum chemistry. Prerequisites: a C or better in Physics 202 or 212, a C or better in Chemistry 122, a C or better in Mathematics 116. Prerequisite for 322: a C or better in 321. Lecture, four hours.

325L, 325R. Advanced Integrated Lab I.  4 cr.

Students consolidate basic laboratory technique and learn to use and interpret results from modern chemical analytical instrumentation. Experiments are open-ended allowing students to approach problems in a genuine scientific format of designing their approach to defined problems, executing the experiments, and interpreting the results. Topic areas are drawn from inorganic synthesis, kinetics, chemical analysis, biochemical analysis, and spectroscopy. Techniques include chromatography, spectroscopy, electrophoresis, computational methods and statistics. Students will begin learning to interpret and communicate their work. Prerequisite: a C or better in 301 or 321, and a C or better in 423. Laboratory, eight hours; recitation, two hours.

371W. Forensic Chemistry Lab I.  2 cr.

Students will learn the basic techniques used in a forensic laboratory. They will use microscopy, IR, visible spectroscopy, and GC-MS to analyze hair, fabrics, fingerprints, and glass fragments. They will learn to detect metal residues, flammable liquids, and poisons. Laboratory, six hours. Prerequisite: a C or better in 423

372W. Forensic Chemistry Lab II.  2 cr.

Students will become very familiar with the main tools in the forensic laboratory; IR and GC-MS. They will develop the knowledge and ability to apply these techniques to solve complicated forensic analysis problems. Prerequisite: a C or better in CHEM 371W. Laboratory, six hours

391. Chemistry Experience in China.  3 crs.

This course provides an in-depth three-week scientific and cultural experience in China facilitated through Duquesne University and the Chinese Association of Science and Technology. Students will travel to several universities in China and work in seminars or small groups with the opportunity to (1) communicate orally and in writing in topics such as environmental science and pollution abatement; (2) acquire appropriate learning skills for collective laboratory work; (3) become familiar with global scientific issues through actively participating in scientific presentations. Students must participate in pre-trip seminars during the spring semester, in the August three-week trip including all activities during the trip, in the writing of reports to include in the trip summary document, and in a post-trip presentation to the public. Pass/Fail.

401. General Biochemistry I.  3 cr.

An introduction to modern biochemistry at the molecular level. The course includes discussion of the structure and function of proteins, the chemical mechanisms and regulation of enzyme catalysis, biomembrane structure and function, the structure and metabolism of carbohydrates, and the bioenergetics of ATP synthesis and utilization. Prerequisite: a C or better in 212 or 212H. Lecture, three hours.

402. General Biochemistry II.  3 cr.

This course is a continuation of CHEM 401. The course presents an overview of the metabolic transformations of fatty acids, complex lipids, amino acids, and the purine and pyrimidine nucleotides. The second half of the course offers a discussion of the molecular basis of genetics, including DNA and RNA metabolism, protein biosynthesis, and an introduction to the biochemical basis of recombinant DNA methodology. Prerequisite: a C or better in 401. Lecture, three hours.

412. Inorganic Chemistry II.  3 cr.

The course heavily draws upon the basic principles of inorganic chemistry and applies them to transition metal chemistry. Topics include organometallic compounds, coordination compounds, point group symmetry, ligand field theory, and its applications, as well as electronic spectra, inorganic reaction mechanisms, and extended solids. Prerequisite: a C or better in 312 and 322. Lecture, three hours

423. Analytical Chemistry.  3 cr.

Theoretical and practical training in modern chemical analysis with emphasis on instrumental methods. Corequisite: 321. prerequisite: a C or better in 230L. Lecture, three hours.

425L, 425R Advanced Integrated Lab II.  4 cr.

Students work in small teams on real research problems. Each team contributes to a single problem, and several chemical and biochemical problems may be studied over the course of a semester. Examples include determining the expression of quality markers and antioxidants in wine production, problems of self assembled biomolecules, protein structure-function relationships, lipid reactivity and physiochemical behavior, etc. Problems are designed according to student career interests. They will also learn advanced data analysis and communication skills. Prerequisite: a C or better in 325L, 325R. Laboratory, 8 hours; recitation, two hours.

475. Senior Seminar.  1 cr.

A capstone course exhibiting the interdisciplinary nature of chemistry. Each faculty member will provide a perspective on how their discipline contributes to the frontiers of science.

475H. Honors Senior Seminar. 1cr. The primary goal of this class is the construction of a high quality Honors Thesis and manuscripts for submission to professional science journals. The students will learn to access and use scientific references, journals and electronic information as they prepare their Thesis. Students will incorporate different types of multimedia in presenting a Department wide defense of their Thesis project. Prerequisite: 325L and entry into the Honors program.

490. Undergraduate Research. Maximum 2 cr./ Semester

Selected students work on a research problem under the direction of a staff member.

490H. Honors Undergraduate Research. Maximum 2 cr./Semester

Exceptional undergraduates that have been accepted into the Department of Chemistry and Biochemistry Honors program will perform advanced level research with the goal of producing sufficient quality data to enable them to prepare an Honors Thesis and manuscripts for publication.