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Neurodegenerative Undergraduate Research Experience (NURE)

2018 NURE Monday, May 21 to Friday, July 27, 2018

DUE DATE FOR Summer 2018 NURE is February 15, 2018 for external applicants and March 1, 2018 for Duquesne University Students. 

Program Description

We welcome undergraduate biology, pharmacy, chemistry, biochemistry, psychology, and health science majors interested in neuroscience and neurodegenerative research to apply to the Neurodegenerative Undergraduate Research Experience (NURE) summer program. Applicants should apply through the 2017 Summer Undergraduate Research Program. This program has been funded in part by the generous support of the Duquesne University Charles Henry Leach II Fund.

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Program Objectives

The innovation of this program centers on involving students in basic science and clinical neuroscience research at the undergraduate level. The objectives of this program are to:

  • Provide a means for students interested in biomedical research  to participate in a full-time mentored research experience.
  • Connect undergraduate students with faculty mentors working on neuroscience-specific basic science questions.
  • Stimulate neuroscience and neurodegenerative research at Duquesne University by bringing together experts in the neurobiology, chemistry, drug discovery and clinical fields with excellent undergraduate researchers.
  • Explore the physiological, chemical, and psychological components of neuroscience disorders, treatments, and research.
  • Aid in the professional growth of undergraduate students and faculty mentors through interactions with individuals who are currently living with neurodegenerative disorders.
  • Provide effective and meaningful discussions and training in ethics related to both the treatment and study of neurodegenerative disorders.

Program Details

Each undergraduate fellow will be paired with a faculty mentor for the summer. This faculty mentor will help guide the student through a summer research topic that will explore a timely and important question in the field of neuroscience. Students will work in the research lab for the majority of their time in the summer. In addition, students will:

  1. Participate in a 6-week long ethics mini-course with the rest of the Summer Undergraduate Research Program.
  2. Attend a once per month journal club where they will discuss primary literature with faculty, students, and clinicians.
  3. Have the opportunity to interact with individuals that are currently living with neurodegenerative conditions such as Parkinson's Disease and Alzheimer's Disease. These interactions will help students understand the personal and practical aspects of managing neurodegenerative disease. 
  4. Use a "neuroscience empathy kit" developed here at Duquesne that simulates some of the sensations experienced by individuals living with neurodegenerative disorders.

Eligibility and Application Requirements

There are two parts to the application:

1. Statement of Goals: In 2 pages or less (1) describe your interest in scientific research (2) describe your interest in pain or pain research and (3) tell us about your future scientific goals and how the program will help you achieve those goals.

2. Resume or Curriculum Vitae (CV): (No page limit) Please include your educational background, extracurricular activities, previous research experience, and publications/presentations (if any).

All undergraduate science major students are eligible to apply for the NURE. However, students must identify a research mentor and neuroscience-specific project in order to be considered for the program. A list of researchers at Duquesne University that are involved in neuroscience research can be found below. 

We particular encourage both internal and external applicants from under-represented groups in science. No prior experience in research is necessary but a specific interest in neuroscience must be clear.

If you are interested in being considered for the NURE program, please indicate so in the main 2018 Summer Undergraduate Research Application. Application to the NURE program does not exclude students from being considered for the main 2018 Summer Undergraduate Research Program or the Pain Undergraduate Research Experience (PURE)

Application due dates:  External students - February 15, 2018; Duquesne Students - March 1, 2018

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NURE Faculty 


Please identify and contact faculty prior to submitting your application

Faculty Member Department Research Area
Jane Cavanaugh, Ph.D. Pharmaceutical Sciences Age-related neurodegeneration
Michael Cascio, Ph.D. Chemistry and Biochemistry Structural characterization of ion channels and transporters
Elena V. Donoso Brown, Ph.D., OTR/L Occupational Therapy Assessment of impairments in neurological populations including stroke, traumatic brain injury, and Parkinson's disease
Linda Garand, Ph.D., GCNS-BC Nursing Promoting the mental health and quality of life of older adults; design and conduct of randomized clinical trials of psycho educational interventions
Jelena M. Janjic, Ph.D. Pharmaceutical Sciences Nanoparticles and neuroinflammation
Benedict J. Kolber, Ph.D. Biological Sciences Study the higher control of chronic neuropathic pain and interaction with stress adaptation
Matthew Kostek, Ph.D. Physical Therapy Treatment therapy to reduce inflammation, increase utrophin and improve function in Duchenne Muscular Dystrophy
Rebecca Kronk, Ph.D., MSN, CRNP Nursing Investigate sleep in children with fragile X syndrome
Alexander Kranjec, Ph.D. Psychology Behavioral methods, neuroimaging (fMRI) and non-invasive brain stimulation (tDCS) in normal participants, and lesion analysis methods in patients with focal brain damage
David Lapinsky, Ph.D. Pharmaceutical Sciences Rational design and synthesis of clickable photoaffinity ligands as chemical probes for understanding CNS drug-binding sites
Rehana K. Leak, Ph.D. Pharmaceutical Sciences Study mechanisms underlying the pathology of neurodegenerative disorders and test potential therapies
Rita Mihailescu, Ph.D. Chemistry and Biochemistry Protein-RNA interactions in Fragile X syndrome and ALS/FTD
Rachael Neilan, Ph.D. Mathematics and Computer Science Computational modeling of neuronal responses in chronic pain
Allyson O'Donnell, Ph.D. Biological Sciences β-arrestins as critical regulators of G-protein coupled receptors
Lauren A. O'Donnell, Ph.D. Pharmaceutical Sciences Study how the anti-viral
immune response impacts on development of neural cells during CNS infections
Kyle Selcer, Ph.D. Biological Sciences Role of estrogens and androgens 
Kevin J. Tidgewell, Ph.D. Pharmaceutical Sciences Drug discovery from marine cyanobacteria for CNS disorders
Sarah E. Wallace, M.A., Ph.D. Speech Language Pathology Research on compensatory strategies for individuals with neurogenic communication disorders (e.g. stroke or TBI)
Sarah Woodley, Ph.D. Biological Sciences Mechanisms of environmental stressors on amphibian neuroplasticity

NURE Alumni

2017

Student Name (major) Home Institution Faculty Mentor
Josh Baktay (Math and CS) Duquesne University Dr. Rachael Neilan (Math and CS)
Abigail Cox (Biology) Duquesne University Dr. Benedict Kolber (Biology)
Jordan Allen (Biochemistry) Hamilton College Dr. Matthew Kostek (Physical Therapy)
Linedia Masson (Biology) Florida Memorial University Dr. Kevin Tidgewell (Pharmacy)
Brionna Nelson (Biology) Duquesne University Dr. Jan Janecka (Biology)
Janique Miller (Biology) Florida Memorial University Dr. Michael Cascio (Chemistry)
Makenzie Woltz (Biology) Clarion University Dr. Lauren O'Donnell (Pharmacy)
Paul Zakutansky (Biochemistry) Duquesne University Dr. Rita Mihailescu (Chemistry)

2017 PURE and NURE Fellows