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Duquesne Students to Share Their Research in Harrisburg

Duquesne University Times

Two Duquesne students will be among the university students statewide presenting their research in the state Capitol on Tuesday, March 3.

"Undergraduate Research at the Capitol-Pennsylvania gives our students and faculty a chance to share their work and its potential impact with state legislators, policymakers and peer research institutions across Pennsylvania," said Dr. Alan W. Seadler, associate academic vice president for research and technology.

Representing Duquesne are:

Benjamin Andrick in the Mylan School of Pharmacy, advised by Dr. Wilson Meng, associate professor of pharmaceutical sciences and principal investigator
Shelby Boord, biology (pre-medicine) major with a minor in Women and Gender Studies, advised by Dr. Sarah Woodley, associate professor of biological sciences.

Andrick's research hypothesizes that the safety and efficacy of biologically similar compounds used to treat rheumatoid arthritis (RA) could have very different results in individual patients, given the patient's medical history of infections, particularly the flu.

His work hypothesizes that:

An RA patient's immune system can treat the biologically based compounds intended to help them as invaders, neutralizing any positive impact.
Three prominent immune genotypes in RA patients, which respond to similar amino acid sequences in the flu virus and the helpful compound, could react in a way that would block the compound's positive effects.

A matrix could be used by the U.S. Food and Drug Administration to help determine individual patient risk, clinical and economic outcomes. Besides Meng, pharmacy faculty members Drs. Lauren O'Donnell, Khalid Kamal and Pam Koerner and undergraduate Brianna Cauley also contributed to this work.

References:
Duquesne University Times (excerpt)
newswise

Duquesne University

Founded in 1878, Duquesne is consistently ranked among the nation's top Catholic universities for its award-winning faculty and tradition of academic excellence. Duquesne, a campus of nearly 9,500 graduate and undergraduate students, has been nationally recognized for its academic programs, community service and commitment to sustainability. Follow Duquesne University on Facebook, Twitter and Instagram.
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