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Dr. Skip Kingston

Skip Kingston

Professor
Bayer School of Natural and Environmental Sciences
Chemistry & Biochemistry

332A Mellon Hall
Phone: 412.396.5564
kingston@duq.edu

Education:

B.A, M.S., Indiana University of Pennsylvania
Ph.D., American University
Bio

Dr. H. M. (Skip) Kingston is Professor of Analytical Chemistry and dually appointed in the Chemistry and Biochemistry Department and the Environmental Research and Education Center, at Duquesne University in Pittsburgh, PA.

Dr. Kingston received his B.S. degree in chemistry education, an M.S. degree in analytical chemistry from Indiana University of Pennsylvania, and his Ph.D. in analytical chemistry and environmental management from the American University.

Dr. Kingston is also the Director of a focused research center at Duquesne University in mass spectrometry and analytical chemistry. In 2003, Dr. Kingston also became the Chief Technical Officer of Applied Isotopes Technologies Inc., a company requested to be started by the U.S. EPA to support new measurement methods based on patented methods requiring master isotopic standards. From 1976 to 1991, he was a Supervisory Research Chemist in the Inorganic Analytical Research Division of the National Institute of Standards and Technology (NIST). From 1987 to 1991, he conceived and headed the Consortium on Automated Analytical Laboratory Systems (CAALS) which was dedicated to developing automated analytical standards for US measurements and funded by 14 US industries and national laboratories inside the NIST. In 1984-1985, Dr. Kingston was Congressional Science Fellow where he initiated the scientific inquiry and hosted two Congressional hearings that led to the establishment of the U.S. Radon Laws that are estimated to prevent 45,000 bronchial cancer deaths each year.

For the past several years, Dr. Kingston has been actively involved in developing and advancing the areas of speciated isotope dilution mass spectrometry, a definitive measurement method used in environmental health measurements for human diseases. The focus of the current applications are the establishment of a quantitative physical test for autism, definitive environmental quantification of toxins to permit action and homeland defense measurements. He also has pioneered methods in automated and microwave analysis through basic research and methods development. He has invented and authored dozens of standard methods for EPA, NCCLS, SEMI, the U.S. Government and other organizations.

Since 1987, he has received numerous awards for his pioneering work in several areas, including the Kaufman award in biology, chemistry and physics in 2009 and the 1996 R&D 100 Award for invention and development of Speciated Isotope Dilution Mass Spectrometry (SIDMS) adopted in 2008 as a national standard method by the U.S. EPA, the 1987 IR 100 Award for development of the microwave dissolution, the 1988 "Pioneer in Laboratory Robotics" award, the 1988 R&D 100 Award for the development of Chelation Ion Chromatography and the 1990 NIST Applied Research Award and the Department of Commerce Bronze Medal in 1990. He holds multiple patents in the field of (SIDMS), mass spectrometry automation, microwave enhanced chemistry, chelation chromatography and has others pending and remains interested in the development and automation of analytical analysis methods for the measurement of environmental human health. His current research is focused on mass spectrometry and its use in autism diagnosis and environmentally related Homeland Security health measurements.

Publications
  1. Scott Faber, John Kern, Timothy Fahrenholz, Mesay Wolle, Logan Miller, H. M. Skip Kingston,
    "Glutathione Reduced and Oxidized Ratio as a Biomarker of Children With Autism"
    In Preparation.

  2. Andrew Boggess, Scott Faber, John Kern, Logan Miller, H.M. Skip Kingston, "Mean Serum-Level
    of Common Organic Pollutants is Predictive of Behavioral Severity in Children with Autism
    Spectrum Disorders" Nature, Scientific Reports, 6:26185, DOI: 10.1038/srep26185, 2016.

  3. StefanieMädler a, AaronTodd a, H.M. "Skip" _Kingston b, MattPamuku c, FengrongSun a, Cindy
    Tat a, RobertJ.Tooley a, TeresaA.Switzer a, VasileI.Furdui "Ultra-trace level speciated isotope
    dilution measurement of Cr(VI) using ion chromatography tandem mass spectrometry in
    environmental waters", 156-157 104-111, Talanta, 2016.

  4. Stefanie Mädler1,2, Fengrong Sun1, Cindy Tat1, Nadya Sudakova1, Peter Drouin1,nRobert J.
    Tooley1, Eric J. Reiner1,3, Teresa A. Switzer1, Richard Dyer4, H. M. Skip Kingston5, Matt
    Pamuku6, Vasile I. Furdui1, Trace-Level Analysis of Hexavalent Chromium in Lake Sediment
    Samples Using Ion Chromatography Tandem Mass Spectrometry" Journal of Environmental
    Protection, 7, 422-434, 2016.

  5. Christopher Bradburne, PhD*; David Graham , PhD†; H. M. Kingston , PhD‡; MAJ Ruth Brenner
    §; Matt Pamuku , BA∥;Lucy Carruth , PhD*, Overview of ‘Omics' technologies for Military
    Occupational Health Surveillance and Medicine" DOI: http://dx.doi.org/10.7205/MILMED-D-15-
    00050, Vol. 180, No. 10S, pp. 34-48 2015.

  6. Renee Dufault*1,2, Zara Berg2, Raquel Crider1,3, Roseanne Schnoll1,4, Larry Wetsit2, Wayne
    Two Bulls2, Steven G. Gilbert1,5, H.M. "Skip" Kingston6, Mesay Mulugeta Wolle6, G.M. Mizanur
    Rahman6 and Dan R. Laks7 "Blood inorganic mercury is directly associated with glucose
    levels in the human population and may be linked to processed food intake" Integrative Molecular
    Medicine, doi: 10.15761/IMM.1000134, Volume 2(3): 166-179, 2015.

  7. Rebecca L. Wagner, Andrew J. Boggess, Stephanie J. Wetzel, H.M. Skip Kingston, "Sensitive
    and stable pre-calibrated solid-phase extraction columns for environmental and forensic
    quantification using isotope dilution mass spectrometry" Journal - Analytical Methods, Royal
    Society of Chemistry, 7, 4285, DOI: 10.1039/c5ay00443h, 2015.

  8. Scott Faber, Andrew J. Boggess, H. M. Skip Kingston, "A Cleanroom Sleeping Environment's
    Impact on Markers of Oxidative Stress, Immune Dysregulation, and Behavior in Children with
    Autism Spectrum Disorders" - medical journal - BMC Complementary and Alternative Medicine,
    20 "Kingston CV," Cumulative CV
    15:71 (doi:10.1186/s12906-015-0564-0), 2015.

  9. Andrew J. Boggess, H. M. Skip Kingston, Scott Faber, "Using finger-stick blood collection in the
    quantification of organic pollutants in whole blood: an upper-level undercarriage Laboratory"
    completed manuscript to be submitted to J. Chem. Ed. Draft. In IRB Review.

  10. Andrew J. Boggess, G. M. Mizanur Rahman, Matt Pamuku, Scott Faber, H. M. Skip Kingston, "An
    accurate and transferable protocol for reproducible quantification of organic pollutants in human
    serum using direct isotope dilution mass spectrometry" Analyst, 2014, 139, 6223-6231.

  11. Timothy Fahrenholz, Mesay Mulugeta Wolle, H M. "Skip" Kingston, Scott Faber, John C. Kern II,
    Matt Pamuku, Logan Miller, Hemasudha Chatragadda and Andreas Kogelnick,"Molecular
    Speciated Isotope Dilution Mass Spectrometric Methods for Accurate, Reproducible and Direct
    Quantification of Reduced, Oxidized and Total Glutathione in Biological Samples" Analytical
    Chemistry, Journal Publication - 2015, 87, 1232-1240, * Corresponding author. DOI:
    10.1021/ac503933t, Publication Date (Web): December 18, 2014.

  12. Mesay M. Wolle,, G.M. Mizanur Rahman, H.M. ‘Skip' Kingston, Matt Pamuku," Speciation
    analysis of arsenic in prenatal and children's dietary supplements using microwave-enhanced
    extraction and ion chromatography-inductively coupled plasma mass spectrometry," Analytica
    Chemica Acta, 818 2014, 23-31.

  13. G.M. Mizanur Rahman,† Mesay Mulugeta Wolle,*,‡ Timothy Fahrenholz,† H. M. "Skip"
    Kingston,‡ and Matt Pamuku† "Measurement of Mercury Species in Whole Blood Using
    Speciated Isotope Dilution Methodology Integrated with Microwave-Enhanced Solubilization
    and Spike Equilibration, Headspace-Solid-Phase Microextraction, and GC-ICP-MS Analysis"
    Analytical Chemistry, 2014, 86, 6130-6137.

  14. Mesay Mulugeta Wolle, G. M. Mizanur Rahman, H. M. Skip Kingston and Matt Pamuku
    "Optimization and validation of strategies for quantifying chromium species in soil based on
    speciated isotope dilution mass spectrometry with mass balance" JAAS on Line- 2014; Cite this:
    DOI: 10.1039/c4ja00133h.

  15. Duquesne "Development of a rapid and sensitive quantification method for opiates in urine by
    high-resolution direct isotope dilution mass spectrometry" Submitted, Journal of Mass
    Spectrometry 2014.

  16. Renee Dufault, Zara Berg, Raquel Crider, Roseanne Schnoll, Larry Wetsit, Wayne Two Bulls,
    Steven Gilbert, H.M. "Skip" Kingston, Mesay Mulugeta Wolle, G.M. Mizanur Rahman, "Blood
    inorganic mercury is directly associated with glucose levels in the human population and may be
    linked to processed food intake" Journal of Integrative Molecular Medicine (DOI:
    10.15761/IMM.1000134) 2015.

  17. Mizanur Rahman, M. Wolle, G.M., Timothy Fahrenholz, H.M. ‘Skip' Kingston, Matt Pamuku
    "Measurement of mercury species in whole blood using headspace solid phase microextraction
    and gas chromatography-inductively coupled plasma mass spectrometry with speciated isotope
    dilution methodology" Journal of Analytical Chemistry, 86, 6130-6137, 2014.

  18. M. Wolle, G.M. Mizanur Rahman, H.M. ‘Skip' Kingston, Matt Pamuku, "Quantification of
    hexavalent and trivalent chromium species in soil using microwave enhanced sample preparation
    and speciated isotope dilution mass spectrometry with mass balance" Published July 7th on the
    web site first printing, Journal of Analytical Atomic Spectrometry, JAAS, 2014.

  19. M. Wolle, Timothy Fahrenholz, G.M. Mizanur Rahman, H.M. ‘Skip' Kingston, Matt Pamuku and
    Damien Browne, "Method development for the redox speciation analysis of iron by assessing
    carry over effects using isotopically labeled analyte analogues" Journal of Chromatography A,
    21 "Kingston CV," Cumulative CV
    1347 96-103, 2014.

  20. M. Wolle, G.M. Mizanur Rahman, H.M. ‘Skip' Kingston, Matt Pamuku, "Speciation analysis of
    arsenic in prenatal and children's dietary supplements using microwave-enhanced extraction and
    ion chromatography-inductively coupled plasma mass spectrometry" Analytica Chimica Acta, 818
    23-31, 2014.