A New Anti-glioma Therapy, AG119: Pre-clinical Assessment in a Mouse GL261 Glioma Model


biomedcentral.com featured a research paper focused on treatment methods for high grade gliomas (HGGs; grades III and IV), which are the most common primary brain tumors in adults. The article was co-authored by Aleem Gangjee and Roheeth Kumar Pavana. AG is a Professor of Medicinal Pharmacy at Duquesne University (DU), and has extensive expertise (over 150 publications and 31 patents) in synthetic medicinal chemistry, computer-assisted drug design, inhibitors of folate metabolizing enzymes, receptor tyrosine kinase inhibitors, anti-mitotic agents, anti-tumor agents, anti-opportunistic infection agents, nucleosides, heterocyclic chemistry and stereochemistry. RP is a PhD candidate in AG's research group at DU, and has expertise in the synthesis of anti-cancer agents. "We would like to thank the National Institutes of Health (CA136944 (AG); CA14021 (AG)) and Duquesne University (Adrian Van Kaam Chair in Scholarly Excellence (AG)) for funding"


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