A New Anti-glioma Therapy, AG119: Pre-clinical Assessment in a Mouse GL261 Glioma Model
biomedcentral.com featured a research paper focused on treatment methods for high grade gliomas (HGGs; grades III and IV), which are the most common primary brain tumors in adults. The article was co-authored by Aleem Gangjee and Roheeth Kumar Pavana. AG is a Professor of Medicinal Pharmacy at Duquesne University (DU), and has extensive expertise (over 150 publications and 31 patents) in synthetic medicinal chemistry, computer-assisted drug design, inhibitors of folate metabolizing enzymes, receptor tyrosine kinase inhibitors, anti-mitotic agents, anti-tumor agents, anti-opportunistic infection agents, nucleosides, heterocyclic chemistry and stereochemistry. RP is a PhD candidate in AG's research group at DU, and has expertise in the synthesis of anti-cancer agents. "We would like to thank the National Institutes of Health (CA136944 (AG); CA14021 (AG)) and Duquesne University (Adrian Van Kaam Chair in Scholarly Excellence (AG)) for funding"
Founded in 1878, Duquesne is consistently ranked among the nation's top Catholic universities for its award-winning faculty and tradition of academic excellence. Duquesne, a campus of nearly 9,500 graduate and undergraduate students, has been nationally recognized for its academic programs, community service and commitment to sustainability. Follow Duquesne University on Facebook, Twitter and Instagram.